| Sr No. | Trends |
| 1 | The Bills are 18-1 SU when played as -10.0 or more Home Favorite Coming off a Win Since 1996 (94.74%) |
| 2 | The 49ERS are 29-2 SU when played as -10.0 or more Home Favorite Total is 42.5 Since 1996 (93.55%) |
| 3 | The 49ERS are 14-1 SU when played as -10.0 or more Home Favorite With 5 Days Off Since 1996 (93.33%) |
| 4 | The 49ERS are 13-1 SU when played as -10.0 or more Home Favorite Coming off a 1 Home Stand Since 1996 (92.86%) |
| 5 | The Bills are 22-2 SU when played as -10.0 or more Home Favoritevs American Conference Opponent Since 1996 (91.67%) |
| 6 | The Bills are 21-2 SU when played as -10.0 or more Home Favorite Coming off vs American Conference Opponent Since 1996 (91.3%) |
| 7 | The Bills are 21-2 SU when played as -10.0 or more Home Favorite After a Conference Game Since 1996 (91.3%) |
| 8 | The Bills are 18-2 SU when played as -10.0 or more Home Favorite With 6 Days Off Since 1996 (90%) |
| 9 | The 49ERS are 9-1 SU when played as Home Team Coming off a Home Win as a Favorite Last 10 Years (90%) |
| 10 | The Vikings are 8-1 SU when played as Home Team Coming off a 1 Winning Streak Last 5 Years (88.89%) |
| 11 | The Under is 2-14-0 for Ravens when played as Away Team Coming off a 1 Road Stand Last 7 Years (87.5%) |
| 12 | The Under is 2-13-0 for Jaguars when played as Home Team With 6 Days Off Last 2 Years (86.67%) |
| 13 | The Under is 2-12-0 for Dolphins when played as a 10 or more Away Underdog After a Division Game Since 1996 (85.71%) |
| 14 | The Under is 2-12-0 for Dolphins when played as a 10 or more Away Underdog Coming off vs AFC East Division Opponent Since 1996 (85.71%) |
| 15 | The Bills are 18-3 SU when played as Home Team Playing in the Month of January Since 1996 (85.71%) |
| 16 | The Bills are 12-2 SU when played as Home TeamComing off a Win over AFC East division opponent Last 5 Years (85.71%) |
| 17 | The Bills are 11-2 SU when played as Home Team Coming off a 1 Home Stand Last 7 Years (84.62%) |
| 18 | The Bengals are 11-2 SU when played as -3.5 to -6.5 Home Favorite With 6 Days Off Last 10 Years (84.62%) |
| 19 | The Under is 2-11-0 for Cowboys when played as 0 to 3.0 Away Favoritevs National Conference Opponent Last 7 Years (84.62%) |
| 20 | The 49ERS are 16-3 SU when played as -10.0 or more Home Favoritevs NFC West Division Opponent Since 1996 (84.21%) |
| 21 | The 49ERS are 16-3 SU when played as -10.0 or more Home Favorite Coming off a 1 ATS Win Since 1996 (84.21%) |
| 22 | The 49ERS are 56-11 SU when played as -10.0 or more Home Favorite Coming off vs National Conference Opponent Since 1996 (83.58%) |
| 23 | The 49ERS are 56-11 SU when played as -10.0 or more Home Favorite After a Conference Game Since 1996 (83.58%) |
| 24 | The Giants are 10-1-1 ATS when played as a 3.5 to 6.5 Away Underdog Coming off a Lost Last 5 Years (83.33%) |
| 25 | The 49ERS are 45-9 SU when played as -10.0 or more Home Favorite Coming off a Win Since 1996 (83.33%) |